Mafauzy et al., 2022. A Randomized, Placebo-Controlled Crossover Study to Evaluate the Effect of a Natural Powder Blend (Mulberry Leaf Extract [MLE], Vitamin D, Chromium, and Fiber) on Postprandial (PP) Metabolic Response in Type 2 Diabetes (T2D). Diabetes; 71 (Supplement 1): 41-LB. Click to read abstract for poster.
Gheldof et al., 2022. Effect of different nutritional supplements on glucose response of complete meals in two crossover studies. Nutrients; 14: 2674. Click to read paper
Thondre et al, 2021. Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomised, double-blind, placebo-controlled study. Nutrition & Metabolism; 18:41. Click to read paper
Wang et al, 2018. Mulberry leaf extract reduces the glycemic indexes of four common dietary carbohydrates. Medicine (2018) 97:34. Click to read paper
Li et al., 2018. Safety evaluation of mulberry leaf extract: acute, subacute toxicity and genotoxicity studies. Regulatory Toxicology and Pharmacology; 95: 220-226. Click to read paper
Lown et al, 2017. Mulberry extract improves glucose tolerance and decreases insulin concentrations in normoglycaemic adults: results of a randomized double-blind placebo controlled study. PLOS ONE. Click to read paper.
Liu et al, 2016. Prevention effects and possible molecular mechanism of mulberry leaf extract and its formulation on rats with insulin sensitivity. PLOS ONE. Click to read paper.
Lown et al, 2016. Mulberry extract Reducose® total blood glucose in normoglycaemic adults. Diabetes UK Annual Conference
Marx et al, 2016. 28-day repeat dose toxicological study of an aqueous extract on Morus alba. L. Int. J. Tox. Click to read paper.
Lown et al, 2015. Mulberry extract to modulate Blood glucose Responses in normoglycaemic adults (MULBERRY) study protocol for a randomized controlled study. TRIALS. Click to read paper.
PYN-IM-007. Impact of Reducose on 13C breath recovery using the 13C sucrose breath test over an eight hour period – a randomized cross-over clinical trial in 18 participants
REDUCE Study (2021): Reducose® mulberry extract dose-range study: understanding the impact on complex meals – a randomised, placebo controlled clinical trial
PYN-IM-006 (2020): Impact of Reducose (1%) on the glycaemic index and glycaemic response of white bread.
PYN-IM-002a, 2014. An open label, single center clinical study to assess the effects of Reducose® (5%) on the glycaemic index of common carbohydrates in an Indian population
The effect of Reducose® on glucose tolerance in normal Wistar rats.
Asai et al. 2011. Effect of mulberry leaf extract enriched with DNJ on post prandial glycaemic control in subjects with impaired glucose metabolism. J. Diab. Inv.
Kim et al., 2015. Mulberry extract improves postprandial glucose response in prediabetic subjects. J. Med. Food.
Kimura et al, 2007. Food grade mulberry powder suppresses elevation of post-prandial blood glucose in humans. J. Agric. Food Chem.
Kojima et al, 2010. Effects of Mulberry leaf extract on blood lipid profiles. J. Clin. Biochem. Nutr.
Chung et al., 2-13. Acute intake of mulberry leaf extract affects postprandial glucose response after maltose loading. J. Func. Foods.
Mudra et al., 2007. Influence of mulberry leaf extract on blood glucose and breath hydrogen response to ingestion of 75g sucrose by type-2 diabetic and control subjects. Diabetes Care.
Nakamura et al., 2009. Suppressive response of confections containing the extractive from leaves of Morus alba on postprandial blood glucose and insulin. Nutr. & Metab.
Jozefczuk et al., 2017. Mulberry leaf extract decreases digestion and absorption of starch in healthy subjects. Adv. Med. Sci.
Phimarn et al., 2017. Meta-analysis of efficacy of Morus alba to improve blood glucose and lipid profile. Eu. J. Nutr.