Private shareholders:
Please write to the company Registrar the name of the company in which you hold shares, giving full details of both your old and new names, and enclose a copy of the Marriage Certificate or Deed Poll. A copy of a Statutory Declaration is also acceptable if it bears both your old and new signatures. If a married lady wishes to revert to her married name after divorce she will need to send a copy of the decree nisi together with her marriage certificate (to confirm her maiden name) or birth certificate if the marriage certificate is not available. Please ensure that you give your old name in exactly the form in which it is recorded on the Register of Shareholders - this can be seen on your share certificate or dividend counterfoil.

Corporate shareholders:
Please write to the Registrar enclosing an original or certified copy of the Certificate of Incorporation on Change of Name.

Please download the Change of Address form and send it to the Registrar, quoting the name of the company (ies) in which you hold shares. You should give your name as it is recorded on the Register of Shareholders, full details of both your old and new addresses and your investor code (which can be found on your share certificate or dividend counterfoil). The form must be signed by all shareholders where indicated.

In the case of a corporate shareholder, the form should be accompanied by a letter on the company's headed notepaper.

Click here to download the software necessary to read the form (pdf).

You can sell your shares through a stockbroker or sharedealing service. There are a variety of services available. Some take orders to buy or sell shares via the internet, many operate telephone or postal dealing services.

The rates of commission charged vary depending on the kind of service that you are looking for. The cheapest way to deal in shares is usually on an 'execution only' basis which means that a broker will act on your instructions to buy or sell but will not give you advice on the merits of the transaction.

If you are administering an estate, you may need to transfer shares into the names of beneficiaries or sell the holding.

The first step is to contact your Registrar who will carry out the necessary action to the register and send you the forms that will need to be completed.

There are two ways of re-registering the holding, depending on the size of the estate.

If the estate is large, you may need to obtain a grant of representation. This is a document that appoints the representatives who will administer the estate. You may need advice from your solicitor on how to go about this or you can contact the Probate Registry (their number is in Yellow Pages or the Phone Book) for more details.

We will then ask you to return the completed forms with an 'office copy' of the grant. This is a copy of the front page of the document which has been sealed by the Probate Registry.

If you are going to transfer the shares, you will need to complete a transfer form and return it to the Registrar with the share certificates for the holding. A certificate in the new name can then be issued.

If the estate is small the procedure may be simpler. Details can be obtained from the Registrar.

If shares were held in joint names, the account can simply be re-registered in the sole name of the other holder. The Registrar will need a photocopy of the death certificate to amend the register and the share certificates so that replacements can be issued in the new name.

A share certificate in your name is evidence of your ownership of shares.

However, with the development of electronic means of trading shares, most corporate investors no longer use share certificates and rely instead on secure systems for exchanging data with the registrar and the London Stock Exchange. Some brokers now offer services which enable you to hold shares in electronic format without needing to have a share certificate. This means that in theory you can deal much faster because there is no need to supply certificates as evidence of ownership, but there is often a charge for this service.

If you lose your share certificate or it has been stolen, you should inform the Registrar immediately. You will need to provide the name of the company in which you are a shareholder, your full name and address, as they are recorded on the Register of Shareholders, and if possible the number(s) of the certificate(s) that is/are missing. Please also state clearly whether the certificate(s) is/are lost or stolen.

We'll then make a note of the lost or stolen certificate and send you a letter of indemnity. In signing and returning this indemnity, you are confirming that if the lost share certificate subsequently comes to light, you will return it to us to be cancelled. You are also required to guarantee that the company, in which you are a shareholder, will not be liable for any loss as a result of issuing the duplicate certificate.

Under some circumstances, for example where the shares represented by the missing certificate(s) are worth more than £100.00 it will be necessary for the Letter of Indemnity to be counter-signed by a guarantor. The Registrar can arrange this for you, but this will attract a further fee

In most cases, you'll need to pay an administration fee before a new share certificate can be sent. Details can be obtained from the Registrar.

If you have already completed a letter of indemnity and sent it back to the Registrar, the original certificate is now invalid. You should send it back to to be cancelled.

If you have not yet returned it, send the letter of indemnity back to the Registrar with a covering letter confirming that you have found the certificate and there is no need for a replacement to be issued.

Increasingly, companies are offering shareholders the choice of receiving Communications such as the notice of meeting electronically instead of by post. To register a preference, you should in the first instance access the website of the Registrar, or contact them directly, in order to tell them of your preferred option for company mailings: e-mail or post.

You should make sure that your e-mail address is always kept up to date. If it is not possible to send your shareholder communications, such as a notification of meeting, electronically because the address you have given us is not recognised, then you will be sent a paper copy of the e-mail by post (usually within 48 hours).

If a company is offering this facility, you will receive details with other information about the meeting. Generally, there are two ways of voting. If you receive a paper proxy form, you can go to the named website, and log on using the code number on the proxy form. You will then be able to confirm your instruction and send it online

You can buy or sell shares through a stockbroker or sharedealing service. There are a variety of services available. Some take orders to buy or sell shares via the internet, many operate telephone or postal dealing services.

The rates of commission charged vary depending on the kind of service that you are looking for. The cheapest way to deal in shares is usually on an 'execution only' basis which means that a broker will act on your instructions to buy or sell but will not give you advice on the merits of the transaction.

If you want to give or sell your shares to someone that you know, you can transfer your holding using a stock transfer form. Please download and complete the form with:

• full name and address details for both transferor (the old owner) and transferee (the new owner),
• the signature of the transferor,
• the name of the Company (referred to as Name of Undertaking) in which the shares are held,
• the type of share (for example Ordinary Shares),
• and the amount to be transferred in both words and figures.

Stamp duty may be payable depending on the type of transfer. As a general rule, if no money is changing hands then the transaction is not liable for Stamp Duty. More information about stamp duty is available on the Inland Revenue's website (for example, more details of exemptions are detailed in chapter 2 of the Stamp Office Manual which can be downloaded from: www.inlandrevenue.gov.uk/so .

Click here to download the software necessary to read the form (pdf).

It is usually possible to transfer shares to someone below the age of eighteen (or sixteen if the company is registered in Scotland) but you should note that this can lead to complications: for example, dividends will be paid only in the name of the shareholder and if you subsequently wish to transfer shares held in the name of a minor, you will need a court order.

Alternatively, you can continue to hold shares in your name on behalf of the minor, segregating them from other shares you may hold by adding a 'designation'. This is a short identifier, usually a few letters long that marks the shares on our records as a separate holding. You can do this by filling in a stock transfer form, completing the form with your name as both transferor and transferee and specifying a designation in the transferee details. When choosing a designation, you must avoid using names and recognisable phrases.

If you sell shares on a register that is maintained by the Registrar, the balance will be updated shortly after the share register is changed, usually within a day of the change. If shares are bought or sold through the market, the share register changes on the 'settlement' date. This is usually five or ten days after the bargain date and is shown on the contract note from the stockbroker or sharedealing service making the trade.

This is a way of holding shares without a share certificate. Instead of registering as a shareholder directly on the register of members, your shares are held on your behalf by a nominee company. You are still the beneficial owner of the shares and instruct the nominee to buy, sell or transfer your holding on your behalf. A corporate nominee is a nominee that is sponsored by a company particularly for its shareholders. Because the nominee has the backing of the company, participants enjoy in practice the same rights as shareholders including receiving dividends and annual reports and playing a part in the company's general meetings.

Holding shares this way has a number of benefits:

Because you do not hold a share certificate, there is no possibility of having to pay a fee to replace it if it goes missing.

Because shares are held electronically, it is possible to transfer or sell shares very quickly.

Because the nominee's name is entered on the register of members instead of yours, your personal details are hidden from public view.

SDRT is a UK tax that may be payable depending on the type of transfer. As a general rule, if no money is changing hands then the transaction is not liable for Stamp Duty. More information about stamp duty is available on the Inland Revenue's website (for example, more details of exemptions are detailed in chapter 2 of the Stamp Office Manual which can be downloaded from: ( www.inlandrevenue.gov.uk/so ).

CDIs are UK securities representing an underlying interest in an overseas security. They are issued on a one-for-one basis so, for example, 500 shares in Mannesmann AG are equivalent to 500 Mannesmann CDIs.

Because CDIs are UK securities, you can receive dividends in sterling and can buy or sell CDIs easily in the UK.

You should note however that if underlying investments are quoted in other currencies, exchange rate movements may affect the value of your investment in pounds sterling.

In the UK, any CREST member can hold CDIs. CREST is the company that settles most UK trades in equities. If you are not a CREST member, you can often hold CDIs through a nominee service.

In accordance with the FSA´s Disclosure and Transparency Rules, the Company hereby notifies the market of the following:

-Phynova´s capital consists of 22,569,684 ordinary shares with voting rights, as disclosed in an announcement on 30th April 2007.

-The Company holds no shares in treasury.

-Therefore, the total number of voting rights in the Company is 22,569,684.

The above figure may be used by shareholders as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, Phynova under the FSA´s Disclosure and Transparency Rules.